WebFertilization by multiple sperm leads to lethal chromosomal number abnormalities, failed embryo development, and miscarriage. In some vertebrate and invertebrate eggs, the so-called cortical reaction contributes to their activation and prevents polyspermy during fertilization. This process involves biogenesis, redistribution, and subsequent … WebAug 12, 2015 · Cortical granule exocytosis (CGE), also known as cortical reaction, is a calcium- regulated secretion that represents a membrane fusion process during meiotic cell division of oocytes. The molecular …
Biochemical heterogeneity, migration, and pre-fertilization release …
WebThe events leading to formation of the fertilization membrane require about one minute. At the point on the outer surface of the sea urchin egg at which a spermatozoan attaches, the thin vitelline membrane becomes … WebApr 9, 2000 · The function and fate of the acrosome is discussed in the next section on fertilization. Structure of the Egg. ... The final structural feature of the egg that serves a critical function during fertilization is a … boy hits car man without skin
The molecular basis of fertilization (Review) - Spandidos …
WebJun 10, 2003 · Abstract. Following fusion of sperm and egg, the contents of cortical granules (CG), a kind of special organelle in the egg, release into the perivitelline space … WebAcrosomal enzymes digest a portion of zona pellucida. 3. Sperm binds to and fuses with oocyte plasma membrane. 4. Sperm nucleus enters cytoplasm of oocyte. 5. Cortical granules release enzymes; zona pellucida becomes fertilization membrane. 6. Sperm and egg pronuclei are enclosed in a nuclear envelope. WebAbstract. An egg-that took weeks to months to make in the adult-can be extraordinarily transformed within minutes during its fertilization. This review will focus on the molecular biology of the specialized secretory vesicles of fertilization, the cortical granules. We will discuss their role in the fertilization process, their contents, how ... guzheng picture